Chylomicrons are large particles that transport dietary fat and cholesterol from the intestines to the liver and other tissues. They are also known as ultra low-density lipoproteins.
How are chylomicrons made?
- The intestines produce chylomicrons from dietary lipids, such as cholesterol and fatty acids
- The size of chylomicrons depends on how much fat is consumed
- A high-fat meal leads to larger chylomicrons
What do chylomicrons do?
- Carry fat-soluble vitamins, cholesterol, and triglycerides from the small intestine to the bloodstream
- Distribute dietary triglycerides to muscle and adipose tissue
- Promote intestinal absorption of lipopolysaccharides
Chylomicronemia
- A condition that can be caused by genetic factors, obesity, diabetes, or certain medications
- Symptoms include abdominal pain, nerve damage, and fatty deposits in the skin
Chylomicron remnants
- Smaller particles that result from lipolytic processes that break down chylomicrons
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