Friday, February 28, 2025

 Chylomicrons are large particles that transport dietary fat and cholesterol from the intestines to the liver and other tissuesThey are also known as ultra low-density lipoproteins. 

How are chylomicrons made? 
  • The intestines produce chylomicrons from dietary lipids, such as cholesterol and fatty acids
  • The size of chylomicrons depends on how much fat is consumed
  • A high-fat meal leads to larger chylomicrons
What do chylomicrons do? 
  • Carry fat-soluble vitamins, cholesterol, and triglycerides from the small intestine to the bloodstream
  • Distribute dietary triglycerides to muscle and adipose tissue
  • Promote intestinal absorption of lipopolysaccharides
Chylomicronemia 
  • A condition that can be caused by genetic factors, obesity, diabetes, or certain medications
  • Symptoms include abdominal pain, nerve damage, and fatty deposits in the skin
Chylomicron remnants 
  • Smaller particles that result from lipolytic processes that break down chylomicrons

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